更新日： 2015/09/07

クロルヘキシジン清拭

Chlorhexidine bathing and health care-associated infections: a randomized clinical trial.

Noto MJ, Domenico HJ, Byrne DW, et al. Chlorhexidine bathing and health care-associated infections: a randomized clinical trial. JAMA. 2015 Jan 27;313(4):369-78. PMID: 25602496

更新日： 2015/01/15

SDD,SODと耐性菌

Effects of decontamination of the oropharynx and intestinal tract on antibiotic resistance in ICUs: a randomized clinical trial.

Effects of decontamination of the oropharynx and intestinal tract on antibiotic resistance in ICUs: a randomized clinical trial.JAMA. 2014 Oct 8;312(14):1429-37. PMID: 25271544

更新日： 2014/08/18

H2ブロッカー vs PPI

Histamine-2 receptor antagonists vs proton pump inhibitors on gastrointestinal tract hemorrhage and infectious complications in the intensive care unit.

MacLaren R, Reynolds PM, Allen RR, et al.Histamine-2 receptor antagonists vs proton pump inhibitors on gastrointestinal tract hemorrhage and infectious complications in the intensive care unit. JAMA Intern Med. 2014 Apr;174(4):564-74. PMID: 24535015

更新日： 2014/01/13

IPCによるDVT予防

Stratified Meta-Analysis of Intermittent Pneumatic Compression of the Lower Limbs to Prevent Venous Thromboembolism in Hospitalized Patients

Kwok M. Ho, MPH, PhD, Stratified Meta-Analysis of Intermittent Pneumatic Compression of the Lower Limbs to Prevent Venous Thromboembolism in Hospitalized Patients. Circulayion. August 27, 2013;128:1003-1020. PMID: 23852609

更新日： 2014/01/06

機械弁とダビガトラン

Dabigatran versus Warfarin in Patients with Mechanical Heart Valves

John W. Eikelboom, M.D., Stuart J. Connolly, M.D.Dabigatran versus Warfarin in Patients with Mechanical Heart Valves. N Engl J Med 2013 Sep 26; 369:1206-1214. PMID: 23991661

更新日： 2013/12/16

脳卒中患者におけるVTE予防戦略

Effectiveness of intermittent pneumatic compression in reduction of risk of deep vein thrombosis in patients who have had a stroke (CLOTS 3): a multicentre randomised controlled trial.

CLOTS (Clots in Legs Or sTockings after Stroke) Trials Collaboration, Dennis M, Sandercock P, et al. Effectiveness of intermittent pneumatic compression in reduction of risk of deep vein thrombosis in patients who have had a stroke (CLOTS 3): a multicentre randomised controlled trial.Lancet. 2013 Aug 10;382(9891):516-24.

更新日： 2013/08/19

血小板の予防輸血

A No-Prophylaxis Platelet-Transfusion Strategy for Hematologic Cancers

Simon J, Stanworth, M.D., et al. A No-Prophylaxis Platelet-Transfusion Strategy for Hematologic Cancers. N Engl J Med 2013; 368:1771-1780. PMID: 23656642

更新日： 2013/06/17

グルタミンと抗酸化剤

A Randomized Trial of Glutamine and Antioxidants in Critically ill Patients

Daren Heyland, M.D., John Muscedere, M.D., et al. A Randomized Trial of Glutamine and  Antioxidants in Critically ill Patients. N Engl J Med 2013; 368:1489-1497 PMID:  23594003

更新日： 2013/05/27

クロルヘキシジン清拭

Effect of Daily Chlorhexidine Bathing on Hospital-Acquired Infection

Michael WC, Deborah SY, et al. Effect of Daily Chlorhexidine Bathing on Hospital-Acquired Infection  N Engl J Med. 2013;368:533-542

更新日： 2011/07/25

ICUにおける多剤耐性菌の感染拡大予防

1）Intervention to reduce transmission of resistant bacteria in intensive care.
2）Veterans Affairs initiative to prevent methicillin-resistant Staphylococcus aureus infections.

1）Huskins WC, Huckabee CM, O'Grady NP, et al. Intervention to reduce transmission of resistant bacteria in intensive care. N Engl J Med. 2011; 364: 1407-18. PMID: 21488763
2）Jain R, Kralovic SM, Evans ME, et al. Veterans Affairs initiative to prevent methicillin-resistant Staphylococcus aureus infections. N Engl J Med. 2011; 364: 1419-30. PMID: 21488764

更新日： 2011/02/02

新世紀のストレス潰瘍予防

Stress ulcer prophylaxis in the new millennium: a systematic review and meta-analysis.

Marik PE, Vasu T, Hirani A, et al. Stress ulcer prophylaxis in the new millennium: a systematic review and meta-analysis. Crit Care Med. 2010; 38: 2222-8. PMID: 20711074

更新日： 2010/05/24

Chlorhexidine-Alcoholとイソジン

Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis

Darouiche RO, Wall MJ Jr, Itani KM, et al. Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis. N Engl J Med. 2010; 362: 18-26. PMID: 20054046

Word（ZIP 圧縮）をダウンロード

更新日： 2010/04/05

鼻腔に潜むS.aureusの殺菌とSSIの予防

Preventing Surgical-Site Infections in Nasal Carriers of Staphylococcus aureus

Bode LG, Kluytmans JA, Wertheim HF, et al. Preventing surgical-site infections in nasal carriers of Staphylococcus aureus. N Engl J Med. 2010; 362: 9-17. PMID: 20054045

PPTデータ（ZIP圧縮）をダウンロード

更新日： 2010/01/20

Esomeprazoleの潰瘍予防

Intravenous Esomeprazole for Prevention of Recurrent Peptic Ulcer Bleeding

Thomson AB. Intravenous esomeprazole for prevention of recurrent peptic ulcer bleeding. Curr Gastroenterol Rep. 2009; 11: 339-41. PMID: 19765360

Wordデータ（ZIP圧縮）をダウンロード

更新日： 2009/09/10

クロルヘキシジンスポンジとカテーテル感染

Chlorhexidine-Impregnated Sponges and Less Frequent Dressing Changes for Prevention of Catheter-Related Infections in Critically III Adults: A Randomized Controlled Trial

Timsit JF, Schwebel C, Bouadma L, et al. Chlorhexidine-impregnated sponges and less frequent dressing changes for prevention of catheter-related infections in critically ill adults: a randomized controlled trial. JAMA. 2009 Mar 25;301(12):1231-41. PMID: 19318651

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