私たちの考えるジャーナルクラブは、参加者が海外文献を和訳して発表し合うというような、単なる“抄読会”とは一線を画します。試験デザインから結論に至るまでの過程を常に批判的な視点でとらえ、同様の、あるいはそれ以上のエビデンスを自分たちの施設で獲得するにはプロトコールのどの部分を手直しすればよいかなど、現場主義に徹した討論の場を提供するのがJSEPTICのジャーナルクラブです。参考までに最近のレビューをお示しします。この臨場感に惹かれたなら、今すぐJSEPTICの門戸を叩いてください。
更新日： 2017/02/13
呼吸不全とリハビリ
Standardized Rehabilitation and Hospital Length of Stay Among Patients With Acute Respiratory Failure: A Randomized Clinical Trial.
Morris PE, Berry MJ, Files DC, et al. Standardized Rehabilitation and Hospital Length of Stay Among Patients With Acute Respiratory Failure: A Randomized Clinical Trial. JAMA. 2016 Jun 28;315(24):2694-702. PMID: 27367766
更新日： 2017/02/13
NPPVでのマスクとヘルメット
Effect of Noninvasive Ventilation Delivered by Helmet vs Face Mask on the Rate of Endotracheal Intubation in Patients With Acute Respiratory Distress Syndrome: A Randomized Clinical Trial.
Patel BK, Wolfe KS, Pohlman AS, et al. Effect of Noninvasive Ventilation Delivered by Helmet vs Face Mask on the Rate of Endotracheal Intubation in Patients With Acute Respiratory Distress Syndrome: A Randomized Clinical Trial. JAMA. 2016 Jun 14;315(22):2435-41. PMID: 27179847
更新日： 2016/10/03
低リスク患者の抜管後のHFNC
Effect of Postextubation High-Flow Nasal Cannula vs Conventional Oxygen Therapy on Reintubation in Low-Risk Patients: A Randomized Clinical Trial.
Hernández G, Vaquero C, González P, et al. Effect of Postextubation High-Flow Nasal Cannula vs Conventional Oxygen Therapy on Reintubation in Low-Risk Patients: A Randomized Clinical Trial. JAMA. 2016 Apr 5;315(13):1354-61. PMID: 26975498
更新日： 2016/07/25
アセタゾラミドとCOPD
Effect of Acetazolamide vs Placebo on Duration of Invasive Mechanical Ventilation Among Patients With Chronic Obstructive Pulmonary Disease: A Randomized Clinical Trial.
Faisy C, Meziani F, Planquette B, et al. Effect of Acetazolamide vs Placebo on Duration of Invasive Mechanical Ventilation Among Patients With Chronic Obstructive Pulmonary Disease: A Randomized Clinical Trial. JAMA. 2016 Feb 2;315(5):480-8. PMID: 26836730
更新日： 2016/07/25
腹部術後の呼吸不全
Effect of Postextubation High-Flow Nasal Cannula vs Conventional Oxygen Therapy on Reintubation in Low-Risk Patients: A Randomized Clinical Trial.
Effect of Noninvasive Ventilation on Tracheal Reintubation Among Patients With Hypoxemic Respiratory Failure Following Abdominal Surgery: A Randomized Clinical Trial.
Hernández G, Vaquero C, González P, et al. Effect of Postextubation High-Flow Nasal Cannula vs Conventional Oxygen Therapy on Reintubation in Low-Risk Patients: A Randomized Clinical Trial. JAMA. 2016 Apr 5;315(13):1354-61. PMID: 26975498
更新日： 2016/06/13
PAVは呼吸器離脱に適したモードか?
A Pilot Randomized Trial Comparing Weaning From Mechanical Ventilation on Pressure Support Versus Proportional Assist Ventilation.
Bosma KJ, Read BA, Bahrgard Nikoo MJ, et al. A Pilot Randomized Trial Comparing Weaning From Mechanical Ventilation on Pressure Support Versus Proportional Assist Ventilation. Crit Care Med. 2016 Jun;44(6):1098-108. PMID: 26807682
更新日： 2015/07/06
ARDSにおける駆動圧と予後
Driving pressure and survival in the acute respiratory distress syndrome.
Amato MB1, Meade MO, Slutsky AS, et al. Driving pressure and survival in the acute respiratory distress syndrome.N Engl J Med. 2015 Feb 19;372(8):747-55.PMID: 25693014
更新日： 2013/09/30
気管切開のタイミング
Effect of Early vs Late Tracheostomy Placement on Survival in Patients Receiving Mechanical Ventilation. The TracMan Randomized Trial
Duncan young, DM, et al. Effect of Early vs Late Tracheostomy Placement on Survival in Patients Receiving Mechanical Ventilation. The TracMan Randomized Trial JAMA. 2013 May 22/29;309(20): 2121-2129. PMID: 23695482
更新日： 2013/05/20
ARDSに対するHFOV
High-Frequency Oscillation in Early Acute Respiratory Distress Syndrome
Niall D. Ferguson, Deborah J. Cook, et al. High-Frequency Oscillation in Early Acute Respiratory Distress Syndrome. N Engl J Med. 2013: 368; 9: 795-805. PMID: 23339639
更新日： 2012/02/27
ARDSにECMO
Extracorporeal membrane oxygenation for ARDS in adults.
Brodie D, Bacchetta M. Extracorporeal membrane oxygenation for ARDS in adults. N Engl J Med. 2011; 365: 1905-14. PMID: 22087681
更新日： 2012/02/21
H1N1インフルエンザとECMO
Referral to an extracorporeal membrane oxygenation center and mortality among patients with severe 2009 influenza A(H1N1).
Noah MA, Peek GJ, Finney SJ, et al. Referral to an extracorporeal membrane oxygenation center and mortality among patients with severe 2009 influenza A(H1N1). JAMA. 2011 Oct 19;306(15):1659-68. Epub 2011 Oct 5. PMID: 21976615
更新日： 2011/11/28
術後のNPPV
Non-invasive ventilation in postoperative patients: a systematic review.
Chiumello D, Chevallard G, Gregoretti C. et al. Non-invasive ventilation in postoperative patients: a systematic review. Intensive Care Med. 2011; 37: 918-29. Epub 2011 Mar 18. PMID: 21424246
更新日： 2011/10/03
早期の理学・作業療法
Feasibility of physical and occupational therapy beginning from initiation of mechanical ventilation.
Pohlman MC, Schweickert WD, Pohlman AS, et al. Feasibility of physical and occupational therapy beginning from initiation of mechanical ventilation. Crit Care Med. 2010; 38: 2089-94. PMID: 20711065
更新日： 2011/09/20
肺エコー
Bedside ultrasound assessment of positive end-expiratory pressure-induced lung recruitment.
Bouhemad B, Brisson H, Le-Guen M, et al. Bedside ultrasound assessment of positive end-expiratory pressure-induced lung recruitment. Am J Respir Crit Care Med. 2011; 183: 341-7. Epub 2010 Sep 17. PMID: 20851923
更新日： 2011/07/11
気切のタイミング2
Early percutaneous tracheotomy versus prolonged intubation of mechanically ventilated patients after cardiac surgery: a randomized trial.
Trouillet JL, Luyt CE, Guiquet M, et al. Early percutaneous tracheotomy versus prolonged intubation of mechanically ventilated patients after cardiac surgery: a randomized trial. Ann Intern Med. 2011 ;154 :373-83. PMID: 21403073
更新日： 2011/06/02
ウイーニングプロトコルは人工呼吸器装着期間を短縮するか？
Use of weaning protocols for reducing duration of mechanical ventilation in critically ill adult patients: Cochrane systematic review and meta-analysis.
Blackwood B, Alderdice F, Burns K, et al. Use of weaning protocols for reducing duration of mechanical ventilation in critically ill adult patients: Cochrane systematic review and meta-analysis. BMJ. 2011; 342: c7237. PMID: 21233157
更新日： 2011/02/02
気管切開は早期にすべきか
Early vs Late Tracheotomy for Prevention of Pneumonia in Mechaniclly Ventilated Adult ICU Patients: A Randomized Controlled Trial.
Terragni PP, Antonelli M, Fumagalli R, et al. Early vs Late Tracheotomy for Prevention of Pneumonia in Mechaniclly Ventilated Adult ICU Patients: A Randomized Controlled Trial. JAMA. 2010; 303: 1483-9. PMID: 20407057
第8回 JSEPTICセミナー
更新日： 2011/01/31
チューブの目盛りか、聴診か、胸部の動きか。-気管挿管の位置-
Endobronchial intubation detected by insertion depth of endotracheal tube, bilateral auscultation, or observation of chest movements: randomised trial.
Sitzwohl C, Langheinrich A, Schober A, et al. Endobronchial intubation detected by insertion depth of endotracheal tube, bilateral auscultation, or observation of chest movements: randomised trial. BMJ. 2010 Nov 9; 341 :c5943. PMID: 21062875
更新日： 2010/08/18
気管切開は早期にすべき？
Early vs Late Tracheotomy for Prevention of Pneumonia in Mechaniclly Ventilated Adult ICU Patients: A Randomized Controlled Trial
Terragni PP, Antonelli M, Fumagalli R, et al. Early vs Late Tracheotomy for Prevention of Pneumonia in Mechaniclly Ventilated Adult ICU Patients: A Randomized Controlled Trial. JAMA. 2010; 303: 1483-9. PMID: 20407057
更新日： 2010/05/24
高いPEEPか低いPEEPか
Higher vs Lower Positive End-Expiratory Pressure in Patients With Acute Lung Injury and Acute Respiratory Distress Syndrome: Systematic Review and Meta-analysis
Briel M, Meade M, Mercat A, et al. Higher vs lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: systematic review and meta-analysis. JAMA. 2010; 303: 865-73. PMID: 20197533
更新日： 2010/04/28
リクルートメント法
Recruitment manoeuvres for adults with acute lung injury receiving mechanical ventilation (Review)
Hodgson C, Keating JL, Holland AE, et al. ecruitment manoeuvres for adults with acute lung injury receiving mechanical ventilation. Cochrane Database Syst Rev. 2009; CD006667. PMID: 19370647
更新日： 2010/03/01
リクルートメント法
Recruitment Maneuvers for Acute Lung Injury
Fan E, Wilcox ME, Brower RG, et al. Recruitment maneuvers for acute lung injury: a systematic review. Am J Respir Crit Care Med. 2008; 178: 1156-63. Epub 2008 Sep 5. PMID: 18776154
