私たちの考えるジャーナルクラブは、参加者が海外文献を和訳して発表し合うというような、単なる“抄読会”とは一線を画します。試験デザインから結論に至るまでの過程を常に批判的な視点でとらえ、同様の、あるいはそれ以上のエビデンスを自分たちの施設で獲得するにはプロトコールのどの部分を手直しすればよいかなど、現場主義に徹した討論の場を提供するのがJSEPTICのジャーナルクラブです。参考までに最近のレビューをお示しします。この臨場感に惹かれたなら、今すぐJSEPTICの門戸を叩いてください。
更新日： 2016/10/03
重症患者介護者の1年後の予後
One-Year Outcomes in Caregivers of Critically Ill Patients.
Cameron JI, Chu LM, Matte A, et al. One-Year Outcomes in Caregivers of Critically Ill Patients. N Engl J Med. 2016 May 12;374(19):1831-41. PMID: 27168433
更新日： 2015/09/07
TAVIから1年後
Clinical outcomes at 1 year following transcatheter aortic valve replacement.
Holmes DR Jr, Brennan JM, Rumsfeld JS, et al. Clinical outcomes at 1 year following transcatheter aortic valve replacement. JAMA. 2015 Mar 10;313(10):1019-28. PMID: 25756438
更新日： 2014/03/10
心停止蘇生後の体温管理
Targeted temperature management at 33°C versus 36°C after cardiac arrest.
Nielsen N, Wetterslev J, Cronberg T, et al. Targeted temperature management at 33°C versus 36°C after cardiac arrest. N Engl J Med. 2013 Dec 5;369(23):2197-206. PMID: 24237006
更新日： 2013/11/05
CPRとAVPとステロイド
Vasopressin, Steroids, and Epinephrine and Neurologically Favorable Survival After In-Hospital Cardiac Arrest A Randomized Clinical Trial
Spyros D. Mentzelopoulos, MD, PhD,. et al. Vasopressin, Steroids, and Epinephrine and Neurologically Favorable Survival After In-Hospital Cardiac Arrest. A Randomized Clinical Trial. JAMA. 2013;310(3):270-279. PMID: 23860985
更新日： 2013/09/30
気管切開のタイミング
Effect of Early vs Late Tracheostomy Placement on Survival in Patients Receiving Mechanical Ventilation. The TracMan Randomized Trial
Duncan young, DM, et al. Effect of Early vs Late Tracheostomy Placement on Survival in Patients Receiving Mechanical Ventilation. The TracMan Randomized Trial JAMA. 2013 May 22/29;309(20): 2121-2129. PMID: 23695482
更新日： 2013/06/17
グルタミンと抗酸化剤
A Randomized Trial of Glutamine and Antioxidants in Critically ill Patients
Daren Heyland, M.D., John Muscedere, M.D., et al. A Randomized Trial of Glutamine and Antioxidants in Critically ill Patients. N Engl J Med 2013; 368:1489-1497 PMID: 23594003
更新日： 2012/11/12
術後トロポニンと予後
Association between postoperative troponin levels and 30-day mortality among patients undergoing noncardiac surgery.
Vascular Events In Noncardiac Surgery Patients Cohort Evaluation (VISION) Study Investigators, Devereaux PJ, Chan MT, Alonso-Coello P, et al. Association between postoperative troponin levels and 30-day mortality among patients undergoing noncardiac surgery. JAMA. 2012 ;307 :2295-304. PMID: 22706835
更新日： 2011/12/26
ARDSから5年後
Functional disability 5 years after acute respiratory distress syndrome.
Herridge MS, Tansey CM, Matté A, et al. Functional disability 5 years after acute respiratory distress syndrome. N Engl J Med. 2011; 364: 1293-304. PMID: 21470008
更新日： 2011/10/24
予後予測因子としてのBUN
Elevation of blood urea nitrogen is predictive of long-term mortality in critically ill patients independent of "normal" creatinine.
Beier K, Eppanapally S, Bazick HS, et al. Elevation of blood urea nitrogen is predictive of long-term mortality in critically ill patients independent of "normal" creatinine. Crit Care Med. 2011; 39: 305-13. PMID: 21099426
更新日： 2011/10/03
低体温療法
Influence of mild therapeutic hypothermia after cardiac arrest on hospital mortality
van der Wal G, Brinkman S, Bisschops LL, et al. Influence of mild therapeutic hypothermia after cardiac arrest on hospital mortality. Crit Care Med. 2011; 39: 84-8. PMID: 20959784
更新日： 2011/09/20
severe sepsisの予後
Long-term cognitive impairment and functional disability among survivors of severe sepsis.
Iwashyna TJ, Ely EW, Smith DM, et al. Long-term cognitive impairment and functional disability among survivors of severe sepsis. JAMA. 2010; 304: 1787-94. PMID: 20978258
更新日： 2011/09/12
BNP測定のoutcome
Meta-analysis: effect of B-type natriuretic peptide testing on clinical outcomes in patients with acute dyspnea in the emergency setting.
Lam LL, Cameron PA, Schneider HG, et al. Meta-analysis: effect of B-type natriuretic peptide testing on clinical outcomes in patients with acute dyspnea in the emergency setting. Ann Intern Med. 2010; 153 : 728-35. PMID: 21135296
更新日： 2011/09/05
ARDSの予後
Functional disability 5 years after acute respiratory distress syndrome.
Herridge MS, Tansey CM, Matté A, et al. Functional disability 5 years after acute respiratory distress syndrome. N Engl J Med. 2011; 364: 1293-304. PMID: 21470008
