私たちの考えるジャーナルクラブは、参加者が海外文献を和訳して発表し合うというような、単なる“抄読会”とは一線を画します。試験デザインから結論に至るまでの過程を常に批判的な視点でとらえ、同様の、あるいはそれ以上のエビデンスを自分たちの施設で獲得するにはプロトコールのどの部分を手直しすればよいかなど、現場主義に徹した討論の場を提供するのがJSEPTICのジャーナルクラブです。参考までに最近のレビューをお示しします。この臨場感に惹かれたなら、今すぐJSEPTICの門戸を叩いてください。
更新日： 2014/04/07
鎮静とせん妄
Sedation and Delirium in the Intensive Care Unit
Michael C. Reade, M.B., B.S., D.Phil., and Simon Finfer, M.D.. Sedation and Delirium in the Intensive Care Unit. N Engl J Med 2014; 370:444-454January 30, 2014. PMID: 24476433
更新日： 2012/11/19
術後せん妄後の認知機能の経過
Cognitive trajectories after postoperative delirium.
Saczynski JS, Marcantonio ER, Quach L, et al. Cognitive trajectories after postoperative delirium. N Engl J Med. 2012 ; 367: 30-9. PMID: 22762316
更新日： 2012/06/18
デクスメデトミジン vs. ミダゾラム or プロポフォール
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Jakob SM, Ruokonen E, Grounds RM, Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials. JAMA. 2012;307:1151-60. PMID: 22436955
更新日： 2011/10/17
ケタミン
Ketamine with and without midazolam for emergency department sedation in adults: a randomized controlled trial.
Sener S, Eken C, Schultz CH, et al. Ketamine with and without midazolam for emergency department sedation in adults: a randomized controlled trial. Ann Emerg Med. 2011 ; 57: 109-114.e2. PMID: 20970888
更新日： 2010/05/24
no sedation protocol
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial
Strøm T, Martinussen T, Toft P. A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial. Lancet. 2010; 375: 475-80. Epub 2010 Jan 29. PMID: 20116842
更新日： 2010/04/05
譫妄と鎮静
Delirium and sedation in the intensive care unit: Survey of behaviors and attitudes of 1384 healthcare professionals
Patel RP, Gambrell M, Speroff T, et al. Delirium and sedation in the intensive care unit: Survey of behaviors and attitudes of 1384 healthcare professionals. Crit Care Med. 2009; 37: 825-32. PMID: 19237884
更新日： 2009/12/25
rapid sequence intubetionにはetomidateかketamineか。
Etomidate versus ketamine for rapid sequence intubation in acutely illpatients: a multicentre randomised controlled trial
Jabre P, Combes X, Lapostolle F, Etomidate versus ketamine for rapid sequence intubation in acutely ill patients: a multicentre randomised controlled trial. Lancet. 2009; 374: 293-300. Epub 2009 Jul 1. PMID: 19573904
更新日： 2009/12/07
オピオイドが原因の便秘にMethylnaltrexone
Methylnaltrexone for Opioid-Induced Constipation in Advanced Illness
Thomas J, Karver S, Cooney GA, et al. Methylnaltrexone for opioid-induced constipation in advanced illness. N Engl J Med. 2008; 358: 2332-43. PMID: 18509120
