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更新日: 2022/11/29

国際医療福祉大学成田病院 救急科 建部 壮 / 井桁 龍平

外傷性出血性ショックに対する病院前救護における蘇生的輸血 RePHILL trial

Resuscitation with blood products in patients with trauma-related haemorrhagic shock receiving prehospital care (RePHILL): a multicentre, open-label, randomised, controlled, phase 3 trial

Nicholas Crombie, et al. Lancet Haematol. 2022 Apr;9(4):e250-e261. PMID:35271808

更新日: 2022/05/17

浦添総合病院 救急集中治療部 鈴木 祥子

COVID-19の退院後血栓予防に対するリバーロキサバンと抗凝固療法なしの比較 MICHELLE trial

Rivaroxaban versus no anticoagulation for post-discharge thromboprophylaxis after hospitalisation for COVID-19 (MICHELLE): an open-label, multicentre, randomised, controlled trial

Eduardo Ramacciotti, et al. Lancet. 2022 Jan 1;399(10319):50-59. PMID:34921756

更新日: 2022/05/10

東京都立多摩総合医療センター 救命救急センター 松村 一希

非心臓手術を行う患者に対してのトラネキサム酸投与 POISE-3 trial

Tranexamic Acid in Patients Undergoing Noncardiac Surgery

P J Devereaux, et al. N Engl J Med. 2022 Apr 2. Online ahead of print. PMID:35363452

更新日: 2021/12/28

東京ベイ・浦安市川医療センター 集中治療科 藤本 裕太郎

成人重症患者の出血時の輸血戦略 ESICMガイドライン

Transfusion strategies in bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine

Alexander P J Vlaar, et al. Intensive Care Med. 2021 Dec;47(12):1368-1392. PMID:34677620

更新日: 2021/04/27

東京ベイ・浦安市川医療センター 集中治療科 中泉 貴之

貧血伴うAMIにおける輸血制限 VS リベラル -REALITY trial-

Effect of a Restrictive vs Liberal Blood Transfusion Strategy on Major Cardiovascular Events Among Patients With Acute Myocardial Infarction and Anemia: The REALITY Randomized Clinical Trial

Gregory Ducrocq, et al. JAMA. 2021 Feb 9;325(6):552-560. PMID: 33560322

更新日: 2020/08/11

浦添総合病院 丸山 晃慶

上部消化管出血に対するトラネキサム酸投与は有効か HALT-IT trial

Effects of a High-Dose 24-h Infusion of Tranexamic Acid on Death and Thromboembolic Events in Patients With Acute Gastrointestinal Bleeding (HALT-IT): An International Randomised, Double-Blind, Placebo-Controlled Trial

HALT-IT Trial Collaborators. Lancet 2020; 395: 1927-36. PMID:32563378

更新日: 2019/12/17

奈良県総合医療センター 紀川 朋子


Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial.

CRASH-3 trial collaborators. Lancet. 2019 Nov 9;394(10210):1713-1723. PMID:31623894

更新日: 2019/04/16

大阪市立総合医療センター 孫 麗香


Adjunctive Intermittent Pneumatic Compression for Venous Thromboprophylaxis

Arabi YM, et al. N Engl J Med. 2019 Feb 18. PMID:30779530

更新日: 2018/09/11

聖マリアンナ医科大学病院 香月洋紀


Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock.

PAMPer Study Group, et al. N Engl J Med. 2018 Jul 26;379(4):315-326. 30044935 PMID:30044935

更新日: 2018/02/13


Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients

Lancet 2018 Jan 13;391(10116):125-132.PMID29126600

更新日: 2017/12/19


Age of Red Cells for Transfusion and Outcomes in Critically Ill Adults.

N Engl J Med.2017 Nov 9;377(19):1858-1867.PMID28952891

更新日: 2017/11/07


Outcomes Associated With Resuming Warfarin Treatment After Hemorrhagic Stroke or Traumatic Intracranial Hemorrhage in Patients With Atrial Fibrillation.

JAMA Intern Med.2017 Apr 1;177(4):563-570 PMID28241151

更新日: 2017/10/31

Atypical HUSの標準的ケアについてのエキスパート・ステートメント

Expert Statements on the Standard of Care in Critically Ill Adult Patients With Atypical Hemolytic Uremic Syndrome.

Chest.2017 Aug;152(2):424-434.PMID28442312

更新日: 2017/06/20

産後出血に対するトラネキサム酸(WOMAN trial)

Effect of early tranexamic acid administration on mortality, hysterectomy, and othermorbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial.

Lancet.2017 May 27;389(10084):2105-2116.PMID28456509

更新日: 2017/01/10


Low-Dose versus Standard-Dose Intravenous Alteplase in Acute Ischemic Stroke

N Engl J Med.2016 Jun 16;374(24):2313-23.PMID27161018

更新日: 2016/12/27


Prevention of Bleeding in Patients with Atrial Fibrillation Undergoing PCI

N Engl J Med.2016 Dec 22;375(25):2423-2434.PMID27959713

更新日: 2016/12/06


Clinical Practice Guidelines From the AABB: Red Blood Cell Transfusion Thresholds and Storage.

JAMA.2016 Nov 15;316(19):2025-2035.PMID27732721

更新日: 2016/07/26


Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial

Lancet.2016 Jun 25;387(10038):2605-13.PMID27178479

更新日: 2016/04/05


Stroke and recurrent haemorrhage associated with antithrombotic treatment after gastrointestinal bleeding in patients with atrial fibrillation: nationwide cohort study

BMJ.2015 Nov 16;351:h5876. PMID26572685