私たちの考えるジャーナルクラブは、参加者が海外文献を和訳して発表し合うというような、単なる“抄読会”とは一線を画します。試験デザインから結論に至るまでの過程を常に批判的な視点でとらえ、同様の、あるいはそれ以上のエビデンスを自分たちの施設で獲得するにはプロトコールのどの部分を手直しすればよいかなど、現場主義に徹した討論の場を提供するのがJSEPTICのジャーナルクラブです。参考までに最近のレビューをお示しします。この臨場感に惹かれたなら、今すぐJSEPTICの門戸を叩いてください。
更新日： 2013/04/15
クロール投与とAKI
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Yunos NM, Bellomo R, Hegarty C, et al. Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults. JAMA. 2012; 308: 1566-72. PMID: 23073953
更新日： 2011/01/31
低リン血症 in ICU
Treatment of hypophosphatemia in the intensive care unit: a review.
Geerse DA, Bindels AJ, Kuiper MA, et al. Treatment of hypophosphatemia in the intensive care unit: a review. Crit Care. 2010; 14: R147. Epub 2010 Aug 3. PMID: 20682049
更新日： 2011/01/31
クロールの評価法
Bench-to-bedside review: Chloride in critical illness.
Yunos NM, Bellomo R, Story D, et al. Bench-to-bedside review: Chloride in critical illness. Crit Care. 2010; 14: 226. Epub 2010 Jul 8.
更新日： 2010/08/18
AKIの栄養療法
Nutritional support for acute kidney injury (Review)
Li Y, Tang X, Zhang J, et al. Nutritional support for acute kidney injury. Cochrane Database Syst Rev. 2010; CD005426. PMID : 20091576
更新日： 2010/08/18
NAGLはAKIの診断、予後判定に有用か？
Original investigations Pathogenesis and treatment of Kidney Disease. Accuracy of Neutrophil Gelatinase-Associated Lipocain (NGAL) in Diagnosis and Prognosis in Acute Kidney Injury: Asystematic Review and Meta Anakysis
Hasse M, Bellomo R, Devarajan P, et al. Accuracy of neutrophil gelatinase-associated lipocalin (NGAL) in diagnosis and prognosis in acute kidney injury: a systematic review and meta-analysis. Am J Kidney Dis. 2009; 54: 1012-24. PMID: 19850388
更新日： 2010/04/05
透析を必要とするAKIでは、フロセミドは腎機能を改善しない。
Furosemide does not improve renal recovery after hemofiltration for acute renal failure in critically ill patients: A double blind randomized controlled trial
van der Voort PH, Boerma EC, Koopmans M, et al. Furosemide does not improve renal recovery after hemofiltration for acute renal failure in critically ill patients: a double blind randomized controlled trial. Crit Care Med. 2009; 37: 533-8. PMID: 19114909
更新日： 2010/04/05
CRRTの流量と予後
Intensity of Continuous Renal-Replacement Therapy in Critically Ill Patients
Bellomo R, Cass A, Cole L, et al; RENAL Replacement Therapy Study Investigators. Intensity of continuous renal-replacement therapy in critically ill patients. N Engl J Med. 2009; 361: 1627-38. PMID: 19846848
